Which class of drugs is typically prescribed for managing chronic heart failure?

ACE inhibitors are a cornerstone in the treatment of chronic heart failure due to their ability to alleviate the symptoms and improve the prognosis of patients with this condition. They work by inhibiting the angiotensin-converting enzyme, which leads to a decrease in the levels of angiotensin II, a potent vasoconstrictor. The reduction in angiotensin II results in vasodilation, lower blood pressure, and decreased workload on the heart. Additionally, ACE inhibitors help to reduce fluid overload, improve cardiac output, and ultimately decrease hospitalization rates associated with heart failure.

While diuretics are also commonly used in managing heart failure, their primary role is to relieve symptoms related to fluid retention rather than address the underlying pathophysiology of the condition. Calcium channel blockers are generally not recommended for chronic heart failure patients unless they have any accompanying hypertensive crises, as they do not offer the same benefits and may even hinder cardiac functioning in some cases. Anticoagulants, while important in preventing thromboembolic events in certain patients, do not directly contribute to heart failure management. Thus, among the options provided, ACE inhibitors are the most beneficial and appropriate choice for managing chronic heart failure.