What is a common adverse effect associated with long-term use of corticosteroids?

Long-term use of corticosteroids commonly leads to weight gain due to several factors. Corticosteroids can stimulate appetite, causing individuals to consume more calories than they typically would. Additionally, these medications can cause changes in metabolism and fat distribution, resulting in an increase in body weight. This weight gain is often seen as a redistribution of fat to the face, abdomen, and neck, leading to the characteristic "moon face" appearance in some patients.

While hair loss, skin rash, and increased energy may occur due to various reasons or in response to different medications, they are not typical adverse effects associated specifically with prolonged corticosteroid use. In contrast, weight gain is a well-documented side effect, especially when corticosteroids are used for extended periods. Understanding these effects is crucial for managing the health of patients requiring corticosteroid therapy and for providing education on potential lifestyle modifications to mitigate weight gain.