What is a common adverse effect of taking rifampin?

Rifampin is known for its ability to stain bodily fluids, particularly urine, with a distinctive orange color. This effect is a result of rifampin's chemical properties, which lead to its metabolites being excreted in urine, causing this alteration in coloration. The orange urine effect is well documented and is often a topic of discussion in clinical settings, as it is important for patients to be informed about this benign, but prominent, side effect to avoid unnecessary concern.

The other potential responses, such as green-colored urine, cloudy urine, or painful urination, are not characteristic adverse effects associated specifically with rifampin. Green urine might be linked to medications such as propofol, while cloudy urine could indicate urinary tract infections or other conditions unrelated to rifampin. Painful urination is a symptom rather than an adverse effect of this medication. Thus, recognizing the orange discoloration of urine as a side effect is key in understanding rifampin's profile and managing patient expectations during treatment.