If a client develops wheezing after receiving ampicillin, which medication order should the nurse question?

In this scenario, the development of wheezing after receiving ampicillin indicates a likely allergic reaction, which raises concerns about cross-reactivity with other beta-lactam antibiotics. Cefaclor, like ampicillin, is a cephalosporin and belongs to the same class of antibiotics. Given that allergic reactions can be similar across this class, questioning the order for cefaclor is prudent in order to avoid potential exacerbation of the client's wheezing and allergic response.

On the other hand, amoxicillin, although also a penicillin-type antibiotic (similar to ampicillin), may be questioned based on the specifics of the client's allergic profile and history. Azithromycin and clindamycin, however, are not related to the penicillin or cephalosporin class and typically do not pose the same risk of cross-reactivity. Therefore, while one might still need to evaluate all options carefully based on the client’s allergies, clindamycin and azithromycin could be safer alternatives in this situation.